基本情況
馬愛(ài)軍，男，甘肅臨洮人，中共黨員?，F(xiàn)任五邑大學(xué)藥學(xué)與食品工程學(xué)院專(zhuān)任教師，研究生處副處長(zhǎng)。
聯(lián)系方式
地址：廣東省江門(mén)市蓬江區(qū)東成村22號(hào) 五邑大學(xué)藥學(xué)與食品工程學(xué)院
郵編：529020
郵箱：[email protected]
工作經(jīng)歷
2023年11月至今，五邑大學(xué)，藥學(xué)與食品工程學(xué)院，碩士生導(dǎo)師
2018年7月-2023年11月，五邑大學(xué)，生物科技與大健康學(xué)院，碩士生導(dǎo)師
2013年7月-2018年6月，美國(guó)德克薩斯大學(xué)西南醫(yī)學(xué)中心（導(dǎo)師：Joseph Ready），博士后
教育及學(xué)習(xí)經(jīng)歷
2008年9月-2013年 6月，蘭州大學(xué)化學(xué)化工學(xué)院（導(dǎo)師：涂永強(qiáng)院士），博士（有機(jī)化學(xué)）
2007年7月-2008年8月，蘭州大學(xué)，化學(xué)化工學(xué)院（導(dǎo)師：涂永強(qiáng)院士），研究助理
2006年7月-2007年6月，中國(guó)科學(xué)院上海有機(jī)化學(xué)研究所（導(dǎo)師：林國(guó)強(qiáng)院士），研究助理
2002年9月-2006年6月，蘭州大學(xué)化學(xué)化工學(xué)院，學(xué)士（化學(xué)）
主要研究方向
天然產(chǎn)物全合成
具有生物活性藥物小分子的設(shè)計(jì)與合成
發(fā)表學(xué)術(shù)論文
24 Fan-Xiao Meng, Xing-Yu Wang, Ka Lu, Ju-Song Yang, Ai-Jun Ma, Zhang Fu-Min, Bao Du, Yong-Qiang Tu, De Novo Synthesis of Atropisomeric Benzofurans via Cu/SPDO Complex Catalyzed Asymmetric Formal [3+2] Annulation, Sci. China Chem., 2024, doi.org/10.1007/s11426-024-2174-x.
23 Yi-Rui Zhang, Zong-Wang Qiu, Zhao-Jie Fu, Shao-Shuai Chen, Han-Peng Pan, Bao Qiong Li, Ai-Jun Ma*, Xiang-Zhi Zhang*, Copper-Catalyzed Sequential C(sp2)?H/C(sp3)?H Annulation of Indoles with Propargylic Alcohols to Access Hydrobenzo[b]carbazoles, Adv. Synth. Catal., 2024, doi.org/10.1002/adsc.202301475.
22 Hui-Hui Zeng, Yu-Qing Wang, Yong-Yu He, Xiao-Ling Zhong, Hongguang Li, Ai-Jun Ma*, and Jin-Bao Peng*, Cooperative Cu/Pd-Catalyzed 1,5-Boroacylation of Cyclopropyl-Substituted Alkylidenecyclopropanes, J. Org. Chem. 2024, 89, 2637–2648.
21 Jing-Yun Zheng（鄭景云）, Ying Luo, Ting-Ting Ou, Xin-Jie Zhang, Yong-Qiang Lao, Na Feng, Jin-Bao Peng, Xiang-Zhi Zhang, Xiaojun Yao, and Ai-Jun Ma*, Acid-Promoted Cyclization of α-Azidobenzyl Ketones through C═N Bond Formation: Synthesis of 6-Substituted Quinoline Derivatives, Org. Lett. 2024, 26, 586-590.
20 Miao-Miao Ji, Peng-Rui Liu, Jun-Dong Yan, Yong-Yu He, Hongguang Li, Ai-Jun Ma*, and Jin-Bao Peng*, Ruthenium-Catalyzed Carbonylation of α-Aminoaryl-Tethered Alkylidenecyclopropanes: Synthesis of Eight-Membered Benzolactams, Org. Lett. 2024, 26, 231-235.
19 Xia Chen（陳霞）, Jianyi Shi, Yuqun Lin, Yibiao Li, Shaohua Jiang, Tianxiang Chen, Zhongzhi Zhu*, Ai-Jun Ma*, Direct syntheses of N-alkyl-2-pyridones using 2-halogenated pyridines, Eur. J. Org. Chem. 2023, e202301184.
18 LIN Siwu（林思武）, ZHAO Lili, SHEN Zhonghui, MA Ai-Jun*, Synthesis of Benzo[6,6]-Spiroketal Compounds, Chin. J. Syn. Chem., 2023, 31, 252-256.
17 Shan-Shan Li（李汕珊）, Li-Li Zhao（趙麗麗）, Min Pan, Na Feng, Bao-Qiong Li, Xiang-Zhi Zhang, Jin-Bao Peng*, and Ai-Jun Ma*, Total Synthesis of (+)-Peniciketal B, Org. Lett. 2023, 25, 8501–8505.
16 Yun Kang, Jin-Liang Lu, Zhi Zhang, Ying-Kang Liang, Ai-Jun Ma*, and Jin-Bao Peng*, Palladium-Catalyzed Intramolecular Heck/Aminocarbonylation of Alkene-Tethered Iodobenzenes with Nitro Compounds: Synthesis of Carbamoyl-Substituted Benzoheterocycles, J. Org. Chem. 2023, 88, 5097–5107.
15 Shengting Xu, Zhongzhi Zhu, Zhendong Yang, Zuyu Mai, Tianxiang Chen, Ai-Jun Ma*, Xiuwen Chen*, Ring-Opening-Recombination Strategy Based on 2-Methylbenzothiazole Salts: Syntheses of Thiazinopyrrole Fused-Ring Derivatives, Adv. Synth. Catal., 2023, 365, 3819-3823.
14 Shan-Shan Li（李汕珊）, Li-Li Zhao（趙麗麗）, Min Pan, Na Feng, Jin-Bao Peng, and Ai-Jun Ma*, K2CO3-Promoted oxy-Michael Addition/Cyclization of α,β-Unsaturated Carbonyl Compounds with Naphthols: Synthesis of Naphthopyrans, Molecules, 2023, 28, 5502.
13 Si-Yuan Lu（盧思遠(yuǎn)）, Hong-Mei Wang, Na Feng* and Ai-Jun Ma*, Total synthesis of bi-magnolignan, RSC Adv., 2023, 13, 8844-8846.
12 HE Li（賀利）, CHEN Mengting, ZHOU Junjie, LUO Lu, FENG Na*, MA Ai-Jun*, Synthesis and Antioxidant Activities of Novel Melatonin Derivatives, Chin. J. Syn. Chem., 2022, 30, 893-901.
11 Zhong-Hui Shen（沈中輝）, Si-Yuan Lu, Jing-Yun Zheng, Xiang-Zhi Zhang, Jin-Bao Peng, Ai-Jun Ma*, Studies toward synthesis of the core skeleton of spiroaspertrione A, Front. Chem., 2022, 10, fchem.2022.1022533.
10 Li He（賀利）, Jing-Jing Du, Meng-Ting Chen, Jun-Jie Zhou, Lu Luo, Baoqiong Li, Xiang-Zhi Zhang, Wen-Zhe Ma, Ai-Jun Ma*, Na Feng*, Synthesis of melatonin derivatives and the neuroprotective effects in Parkinson's disease models of Caenorhabditis elegans, Front. Chem., 2022, 10, 2022.918116.
9 Qi-Ming Liang（梁綺明）, Jing-Yun Zheng, Si-Yuan Lu, Hong-Mei Wang, Lu Luo, Xiang-Zhi Zhang, Jin-Bao Peng, Na Feng, Ai-Jun Ma*, Intramolecular Aerobic Ring Expansion of Cyclic Ketone: A Mild Method for the Synthesis of Medium-Sized Lactones and Macrolactones, Adv. Synth. Catal., 2022, 364, 2152-2156.
8 Shan-Shan Li（李汕珊）, Qi Qin, Zhuang Qi, Li-Miao Yang, Yun Kang, Xiang-Zhi Zhang, Ai-Jun Ma* and Jin-Bao Peng *, Synthesis of disubstituted γ-butyrolactones and spirocyclopropanes via a multicomponent reaction of aldehydes, Meldrum’s acid and sulfoxonium ylides, Org. Chem. Front., 2021, 8, 3069-3075.
7 CHEN Han-qia（陳漢洽）, YANG Meng-yuan, WEI Dong-mei, HE Li, ZHENG Jing-yun, LI Jie-fang, ZHONG Hao-liang, FENG Na, MA Ai-jun*, ZHANG Shu-yu*, ZHANG Kun*, Synthesis of Cinnamic Acid Ester Derivatives of Chrysin, Chin. J. Syn. Chem. 2020, 28, 848-854.
6 Wang, Shaohua, Zhang, Banghong, Chen, Jie, Zheng, Yingying, Feng, Na, Ma, Aijun*, Xu, Xuetao*, Abdullah, M. Asirid, Recent Progress in Synthesis of Polysubstituted Pyrazoles, Chin. J. Org. Chem. 2020, 40, 15-27.
5 Xue-Tao Xu, Xu-Yang Deng, Jie Chen, Qi-Ming Liang, Kun Zhang, Dong-Li Li, Pan-Pan Wu, Xi Zheng, Ren-Ping Zhou, Zheng-Yun Jiang, Ai-Jun Ma*, Wen-Hua Chen*, Shao-Hua Wang*, Synthesis and biological evaluation of coumarin derivatives as aglucosidase inhibitors, Eur. J. Med. Chem. 2020, 189, 112013.
4 Ai-Jun Ma and Joseph M. Ready*, Synthetic Studies on the Kigamicins, Org. Lett. 2019, 21, 1148-1151.
Before 2018
3 Janjira Rujirawanich, Soyeon Kim, Ai-Jun Ma, John R. Butler, Yizhong Wang, Chao Wang, Michael Rosen, Bruce Posner, Deepak Nijhawanc, and Joseph M. Ready*, Synthesis and Biological Evaluation of Kibdelone C and Its Simplified Derivatives, J. Am. Chem. Soc. 2016, 138, 10561-10570.
2 Fu-Min Zhang, Lei Peng, Hui Li, Ai-Jun Ma, Jin-Bao Peng, Jing-Jing Guo, Dengtao Yang, Si-Hua Hou, Yong-Qiang Tu*, and William Kitching, Total Synthesis of the Nominal Didemnaketal A, Angew. Chem. Int. Ed. 2012, 51, 10846-10850.
1 Ai-Jun Ma, Yong-Qiang Tu*, Jin-Bao Peng, Qing-Yun Dou, Si-Hua Hou, Fu-Min Zhang, and Shao-Hua Wang, Total Synthesis of (-)-FR901483, Org. Lett. 2012, 14, 3604–3607.
授權(quán)專(zhuān)利
4 馬愛(ài)軍；李汕珊；趙麗麗；潘敏；馮娜；陳春靈；游松濤 “一種苯并吡喃類(lèi)化合物及其制備方法”，2024.01.12（授權(quán)），中國(guó)，ZL202210881947.2
3 馬愛(ài)軍；賀利；朱瑞燾；周俊杰；陳夢(mèng)婷；文慧心；羅路；馮娜 “一種褪黑激素肉桂酸衍生物及其制備方法”，2023.07.04（授權(quán)），中國(guó)，ZL202210518275.9
2 馮娜；賀利；楊夢(mèng)圓；韋冬梅；馬愛(ài)軍 “一種白楊素肉桂酸酯或其衍生物及其制備方法”，2023.02.17（授權(quán)），中國(guó)，ZL 202010891873.1
1 馬愛(ài)軍；梁綺明；歐婷婷；鄭景云；李鳳萍；盧思遠(yuǎn)；馮娜；陳春靈；游松濤 “2-乙基-3,4-二氫-1(2H)-異喹啉酮的制備方法”，2022.6.21（授權(quán)），中國(guó)，ZL202110688971.X
主持項(xiàng)目
1具有苯并螺環(huán)縮酮和橋環(huán)縮酮化合物peniciketals的合成及構(gòu)效關(guān)系研究
（100萬(wàn) 五邑大學(xué)高層次人才科研啟動(dòng)費(fèi)）（2018-2023 ）
2新型抗腫瘤劑青霉縮酮PeniciketalA、B和C及其衍生物的全合成和活性研究
（20萬(wàn) 廣東省教育廳特色創(chuàng)新項(xiàng)目）（2019-2022）（已結(jié)題）
3新冠肺炎候選特效藥Remdesivir的高效創(chuàng)制研究
（20萬(wàn) 五邑大學(xué)新冠肺炎疫情防控專(zhuān)項(xiàng)）（2019-2022）（已結(jié)題）
4五邑大學(xué)-鶴山市舒柏雅實(shí)業(yè)有限公司聯(lián)合培養(yǎng)研究生示范基地
（10萬(wàn) 廣東省研究生教育創(chuàng)新計(jì)劃項(xiàng)目）（2019-2021）(已結(jié)題)
5廣譜殺蟲(chóng)劑Broflanilide及其衍生物的合成工藝優(yōu)化與活性研究
（45萬(wàn) 廣東省鄉(xiāng)村振興戰(zhàn)略專(zhuān)項(xiàng)資金（“大專(zhuān)項(xiàng)+任務(wù)清單”）項(xiàng)目）（2021-2024）
6分子內(nèi)Schmidt反應(yīng)參與的串聯(lián)策略在天然產(chǎn)物及其衍生物合成中的應(yīng)用
（50萬(wàn) 五邑大學(xué)港澳聯(lián)合研發(fā)基金項(xiàng)目）（2022-2025）
7分子內(nèi)氧化偶聯(lián)反應(yīng)在SpiroaspertrioneA合成中的應(yīng)用及其抑菌活性研究
（10萬(wàn) 廣東省教育廳重點(diǎn)領(lǐng)域?qū)ｍ?xiàng)）（2023-2026）
